• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
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  • 优先权
    • 专利摘要:
    a negative pressure device includes a draper, a capillarity element, a sealing element, a reactor, a chamber, and an air-permeable liquid impermeable element. the drape includes an opening, and is produced from a flexible material that inhibits the passage of liquid and air through the drape other than through the opening. the capillarity element is covered by the drape. the sealing element surrounds the capillarity element and cooperates with the draping to define a closed volume covered by the draping, and surrounded by the sealing element. air inside the closed volume is inhibited from leaving the closed volume other than through the opening. the reactor is configured to react with a gas found in the air to consume the gas. the chamber is in fluid communication with the reactor and the volume closed, via the opening. the chamber is configured to maintain a predefined chamber volume while gas is being consumed from the closed volume. the air-permeable liquid impermeable element is interposed between the chamber and the closed volume, and is configured to prevent liquid from entering the chamber.
    公开号:BR112019018896A2
    申请号:R112019018896
    申请日:2018-04-04
    公开日:2020-04-14
    发明作者:Buan John；D Wolter John；L Middaugh Richard；Manickam Sundar；E Lash Thomas；Wojciechowski Timothy
    申请人:Aatru Medical Llc；
    IPC主号:
    专利说明:

    NEGATIVE PRESSURE DEVICE AND METHOD. BACKGROUND [0001] Negative pressure is a term used to describe a pressure that is below normal atmospheric pressure. Known topical negative pressure devices range from complex wrinkle reduction suction devices to injury therapies that include permeable wound cavity fillers, cover dressings, reasonably air-tight means for sealing against the skin, and drain tubes that connect the wound site, and cavity filling element to the vacuum source, via a fluid collection container.
    [0002] To enable a more prolonged application of topical negative pressure, energized systems, which include a source of vacuum generation, such as a pump, have been developed, and many examples of such systems are used today for skin treatments and treatment proposals. restoration similar to temporary wrinkle removal. Many of these systems, however, are not convenient for users. Such known systems can be large, heavy, noisy, uncomfortable, and not simple for users to apply to initiate a controlled pressure condition. Such known systems also count as an external energy or vacuum source to create topical negative pressure conditions.
    [0003] Such tissue treatment, surgery, and other advanced technical interventions are becoming more common given the occurrence of both an aging population, as well as increasingly compromised patient populations. This trend seems predestined to continue. In injury care, for example, health care professionals are now likely to encounter
    Petition 870190090421, of 12/09/2019, p. 20/85
    2/31 wounds that are difficult to control with complex healing problems. Attempts have been made to produce simpler mechanical devices capable of applying topical and negative pressure to a tissue site. It will be appreciated that such a medical device, due to its relative simplicity of design, would be expected to reduce material costs and assembly costs. For example, attempts have been made to use a hand pump system to apply topical negative pressure to a tissue site. However, such a system fails to enable easier user application, discreet use, and convenient prolonged application of topical negative pressure, and, in fact, re-evacuation is often necessary. These can be serious deficiencies, particularly as many such systems are ideally usable for extended periods, such as overnight.
    SUMMARY [0004] In view of the foregoing, a negative pressure device includes a drapery, a capillarity element, a sealing element, a reactor, a chamber, and an air-permeable liquid-impermeable element. The drape includes an opening, and is produced from a flexible material that inhibits the passage of liquid and air through the drape other than through the opening. The capillarity element is covered by the drape. The sealing element surrounds the capillarity element, and when applied to the skin, it cooperates with the drape to define a closed volume covered by the drape and surrounded by the sealing element. Air inside the closed volume is inhibited from leaving the closed volume other than through the opening. The reactor is configured to react with a gas found in the air to consume the gas. The chamber is in fluid communication with the reactor, and the volume closed, via the
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    3/31 opening. The chamber is configured to maintain a predefined chamber volume, while gas is being consumed from the closed volume. The air-permeable liquid-impermeable element is interposed between the chamber and the closed volume, and is configured to prevent liquid from entering the chamber.
    [0005] A method of treating a tissue site includes attaching a drape to the skin surrounding a tissue site, and covering an element of capillarity. The drape includes an opening, and is produced from a flexible material that inhibits the passage of liquid and air through the drape other than through the opening. The method further includes sealing around the fabric location with a sealing element that cooperates with the drape to define a closed volume covered by the drape and surrounded by the sealing element. The method further includes providing a reactor configured to react with a gas found in the air to consume the gas, and connecting a chamber to be in fluid communication with the reactor and the closed volume. The chamber is configured to maintain a predefined chamber volume, while the reactor consumes gas in the closed volume. The method also includes preventing the liquid from entering the chamber, while the reactor consumes the gas in the closed volume.
    BRIEF DESCRIPTION OF THE DRAWINGS [0006] Figure 1 is a cross-sectional view of a wound dressing assembly.
    [0007] Figure 2 is a top view of the wound cover set shown in Figure 1.
    [0008] Figure 3 is a cross-sectional view of a negative pressure device including an alternative wound cover or tissue assembly, and a pump assembly prior to attaching the pump assembly to the alternative covering assembly.
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    4/31 [0009] Figure 4 is a cross-sectional view of the negative pressure device with the pump assembly attached to the alternative cover assembly.
    [0010] Figure 5 is a cross-sectional view of another set of wound cover or tissue.
    [0011] Figure 6 is a top view of the cover set shown in Figure 5.
    [0012] Figure 7 is a cross-sectional view of an alternative pump set.
    [0013] Figure 8 is a cross-sectional view of another alternative pump set.
    [0014] Figure 9 is a cross-sectional view of another alternative pump set.
    [0015] Figure 10 is a schematic representation of an alternative negative pressure device including a wound cover or tissue assembly, and another alternative pump assembly.
    [0016] Figure 11 is a schematic representation of another alternative pump set for use with the cover set shown in Figure 10.
    [0017] Figure 12 is a schematic representation of another alternative pump set for use with the cover set shown in Figure 10.
    [0018] Figure 13 is a schematic representation of another alternative pump set for use with the cover set shown in Figure 10.
    DETAILED DESCRIPTION [0019] Figure 1 represents a wound cover assembly 10 that includes a wound cover membrane 12 and a removable layer 14. The wound cover membrane 12
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    5/31 is configured to allow at least one of liquid and air to pass through the wound cover membrane 12 from a wound site 16 covered by the wound cover membrane 12 into the environment and vice versa. The removable layer 14 covers at least a portion of the wound cover membrane 12. The removable layer 14 is removable from the wound cover membrane 12 when the wound cover membrane 12 is attached to the skin 18 around the site of the wound. wound 16. The removable layer 14 is configured (for example, made of a particular material or materials) and connected with the wound covering membrane 12, such that air and liquid are inhibited from passing through the wound covering membrane 12 and the removable layer 14 when the wound cover membrane 12 is attached to the skin 18 surrounding the wound site 16, and the removable layer 14 is connected to the wound cover membrane 12. As such, with the removable layer 14 connected with and covering at least a portion of the wound covering membrane 12, the wound covering assembly 10 is not a 'breathable' bandage, and may be referred to as an oc bandage lusive.
    [0020] In the illustrated embodiment, the wound covering membrane 12 is produced from a flexible material, and can be produced from a thin flexible elastomeric film. Examples of such materials include polyurethane or polyethylene films. Adhesive (not shown) is applied to a skin contact surface of the wound covering membrane 12 to secure the wound covering membrane 12 to the skin 18. In some instances, the wound covering membrane 12 allows only air to pass through, whereas, in other examples, the wound covering membrane 12 can allow both air and liquid to pass through. The wound covering membrane 12 can
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    6/31 also include openings (not visible in Figure 1, but another embodiment having at least one opening is described below), and can be configured to inhibit the passage of air and liquid through the wound covering membrane 12 other than through the (s) opening (s). For example, the wound cover membrane 12 can be produced from a material that is impermeable to air and liquid, or the wound cover membrane 12 can be coated with a substance, for example, a hydrogel or a hydrocolloid, or metallized, to inhibit the passage of air and liquid through the wound covering membrane 12 other than through the opening (s). In alternative embodiments, the wound covering membrane 12 can be produced from semipermeable materials that can maintain moisture around the wound site 16, while being permeable to water vapor, oxygen, nitrogen, and other gases.
    [0021] The removable layer 14 covers at least a portion of the wound covering membrane 12. Only a removable layer 14 is shown in Figures 1 and 2, however, more than one removable layer 14 can be provided. For example, a plurality of removable layers 14 where each removable layer 14 covers a portion of the wound covering membrane 12. The removable layer 14 can be produced from a thin flexible film. Examples of such materials include polyurethane and polyethylene films. The removable layer 14 is configured to inhibit the passage of air and liquid through the removable layer 14 when the removable layer 14 is covering and connected with the wound covering membrane 12. The removable layer 14 can be produced from a material that is impervious to air and liquid, or the removable layer 14 can be coated with a substance, for example, a hydrogel or a hydrocolloid, or be metallized so as to be impermeable to air and liquid.
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    7/31 [0022] When the removable layer 14 is removed from the wound cover membrane 12, the wound site 16 is exposed to the environment, albeit through the wound cover membrane 12. When the wound cover membrane 12 is air and permeable liquid, removal of the removable layer 14 can transform the wound cover assembly 10 from an occlusive dressing to a non-occlusive dressing. With the removable layer 14 removed from the wound cover membrane, a pump set (examples described below) can be attached to the wound cover set 10, or to the skin 18, to provide negative pressure to the wound site 16, which will be described in more detail below.
    [0023] The wound cover assembly 10 can also include a sealing element 20 positioned between the skin 18 and the wound cover membrane 12. The sealing element 20 is configured to prevent gas and liquid from passing between the skin 18 and the wound covering membrane 12 when the wound covering membrane 12 is attached to the skin 18, and it is typically in addition to the adhesive used to attach the wound covering membrane 12 to the skin 18. The sealing element 20 operates similarly. to a gasket, and can be produced from a hydrogel material, or any other material that can prevent the migration of air and liquid from the wound site 16 under the wound covering membrane 12 and over the skin 18.
    [0024] With reference to Figure 2, the removable layer 14 can cover at least the portion of the wound covering membrane 12 connected by (inside) the sealing element 20. When the wound covering membrane 12 is air or liquid permeable, removal of the removable layer 14 can transform the wound cover set 10 from an occlusive dressing to a non-occlusive dressing, or 'breathable' dressing.
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    8/31 [0025] The wound cover assembly 10 may also include at least one spacer element 24 covered by the wound cover membrane 12. The spacer element 24 is configured to maintain spacing between the wound cover membrane 12 and the wound site 16 covered by the wound cover membrane 12 when reduced pressure is applied below the wound cover membrane 12 around the wound site 16. The wound cover membrane 12 can be produced from a thin film, which allows that the wound cover membrane 12 conforms to the curves found in the human body, but also tends to be removed from the wound site 16 when negative pressure is applied to the wound site 16 below the wound cover membrane 12. O (s ) spacer element (s) 24 is / are configured to conform to those curves, while maintaining adequate spacing between the cover membrane d and wound 12 and the wound location 16. Examples of such spacer elements will be described in more detail below with reference to alternative embodiments.
    [0026] Referring now to Figure 3, an alternative embodiment of a negative pressure device 26 includes an alternative wound cover set 28 and a pump set 30. The wound cover set 28 shown in Figures 3 and 4 it is similar in function to the wound cover set 10 described above. Referring to Figure 4, the wound cover set 28 is attached to the skin 18 surrounding a wound site 16 to cover the wound site 16. The pump set 30 can then be attached to the wound cover set 28, or the skin 18 around the wound site 16 to provide reduced pressure (typically below atmospheric pressure) to the wound site 16. The wound cover assembly 28 can also
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    9/31 be used to cover the wound site 16 without using the pump set 30. Depending on the materials chosen to produce the wound cover set 28, the wound cover set 28 can provide an occlusive dressing or a dressing non-occlusive to the wound site.
    [0027] Referring back to Figure 3, the wound cover set 28 generally includes a wound contact element, which can include a wound contact layer 32 or a capillary element 34, a drape 36, which can be similar in function to the wound covering membrane 12 described above, and a peeling layer 38, which may be similar to the removable layer 14 described above. Consequently, the wound covering membrane 12 and the drape 36 can be used interchangeably, and the removable layer 14 and the peeling layer 38 can also be used interchangeably. [0028] Drape 36 covers the wound contact element, which can be composed of wound contact layer 32 and capillary element 34. Drape 36 includes at least one opening 40 that extends from a lower (internal) surface ) 44 of the drape 36 to an outer surface 46 of the drape 36. The peeling layer 38 covers the opening 40. The peeling layer 38 is releasable from the draping 36 when the drape 36 is in contact with the covering skin 18 the wound site 16. The peeling layer 38 is connected to the drape 36 in a manner such that air and liquid are prevented from passing through the opening 40 in the drape 36 from the wound site 16 to the environment, and vice versa , when the drape 36 is attached to the skin 18 surrounding the wound site 16, and the peeling layer 38 is connected with the draping 36 covering the opening 40. As such, the draping 36 and the peeling layer 38 can define a volume
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    10/31 closed 42 under the drape 36 and the peeling layer 38 around the wound site 16 when the drape 36 is attached to the skin 18 surrounding the wound site 16, and the peeling layer 38 is connected with the drape 36 covering aperture 40.
    [0029] The wound contact element may include the wound contact layer 32, or the capillarity element 34. As used herein, the word Or 'is not mutually exclusive. The wound contact layer 32 can be produced from an elastomeric material, such as a polymeric material that has rubber-like properties. The wound contact layer 32 can be produced from an elastomeric material which is a thin flexible elastomeric film. Examples of such materials include silver-coated nylon, perforated silicone mesh, or other materials that will not adhere to human tissue. The wound contact layer 32 may include a plurality of openings (not shown) when used in conjunction with the capillary element 34 to allow exudate from the wound location 16 to pass through the wound contact layer 32, and be retained within the capillary element 34. The wound contact layer 32 includes a skin contact side 50, which contacts the skin 18 or the wound site 16 when the wound cover assembly 28 is placed over the wound site 16 (see Figure 2). The wound contact layer 32 also includes an upper side 52 opposite the skin contact side 50 that faces from the wound site 16 when the wound cover assembly 28 is attached to the skin 18 over the wound site 16.
    [0030] The capillary element 34 can be produced from an absorbent material capable of absorbing liquid in order to absorb exudate from the wound site 16. The capillary element 34 includes a skin-facing side 54 that faces the skin 18 and the location of
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    11/31 wound 16 when the wound cover set 28 is attached to the skin 18 over the wound site 16. The capillary element 34 may also include an upper side 56 which is opposite the skin-facing side 54 and forward from the skin 18 when the wound cover assembly 28 is attached to the skin 18 over the wound site
    16. The capillary element 34 can be produced from superabsorbent polymers and absorbent spheres, foams, or natural absorbent materials. The wound cover assembly 28 can also be mounted in a manner, which is described in more detail below, to allow replacement of the capillary element 34 without removing the wound contact layer 32.
    [0031] Drape 36 covers capillary element 34 and wound contact layer 32. Drape 36 can be similar in function to wound cover membrane 12 described above, and wound cover membrane 12 can also be produced from a flexible material, and can be produced from a thin flexible elastomeric film. Examples of such materials include polyurethane and polyethylene films. Drape 36 can be configured to inhibit air and liquid from passing through drape 36 other than opening 40. For example, drape 36 can be produced from a material that is impermeable to air and liquid, or drape 36 can be coated with a substance, for example, a hydrogel or a hydrocolloid, or be metallized, to inhibit air and liquid from passing through the drape 36 other than through the opening 40. In alternative embodiments, the drape 36 can be produced from semipermeable materials which can maintain moisture around the wound site 16, while being permeable to water vapor, oxygen, nitrogen, and other gases.
    [0032] The wound cover set 28 additionally includes a sealing element 60, which operates similarly
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    12/31 to the sealing element 20 described above. Since drape 36 can be produced from a material similar to the flexible film, small air passages can be formed between skin 18 and drape 36 when drape 36 is attached to skin 18 around the wound site 16. The element sealing ring 60 is positioned on the skin contact side 50 of the wound contact layer 32, or on the bottom surface 44 of the drape 36. The sealing element 60 is configured to prevent gas and liquid from passing through any air channels formed between the wound contact layer 32 or the drape 36 and the skin 18, and exiting around a peripheral edge 62 of the drape 36. The sealing element 60 is configured to prevent gas and liquid from passing between human skin 18 and the wound contact layer 32 (or the capillary element 34 if the wound contact layer 32 is not included), or the drape 36 when the drape 36 and the sealing element 60 are applied to the skin 18. The element gasket 60 operates similar to a gasket, and can be produced from a hydrogel material, or any other material that can prevent the migration of air and liquid from the wound site 16 under the drape 36 or the contact layer of wound 32, and on human skin 18. Sealing element 60 is schematically shown in Figures 3 and 4, and can be produced to include multiple rings or deposited in a way to provide a tortuous path through which air and liquid must pass between human skin 18 and wound contact layer 32 (or capillary element 34 if wound contact layer 32 is not included), or drape 36 when drape 36 and sealing element 60 are applied to the skin 18. [0033] The wound cover set 28 may also include at least one spacer element 64 covered by drape 36 when drape 36 is applied to human skin 18 around the
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    13/31 wound site 16. The spacer element 64 is similar to the spacer element 24 described above. The spacer element 64 is configured to maintain spacing between the drape 36 and the wound site 16 covered by the drape 36 when reduced pressure is applied to the closed volume 42. Since the drape 36 can be produced from a flexible material, as the reduced pressure is applied to the closed volume 42, the drape 36 can be removed from the skin 18 and the wound site 16. In situations where the pump set 30 reacts with selected gases in air to remove these selected gases from the closed volume 42 to reduce pressure, having the drape collapse 36 at the injury site 16 can result in pressure in the closed volume 42 that increases towards the environment, which is undesirable for negative pressure injury therapy. The spacer element 64 can be a similar structure or structural element to provide volume control in order to maintain an appropriate spacing between the drape 36 and the wound site 16 when reduced pressure is being applied to the enclosed volume 42. The spacer element 64 it can also be a flexible spiral spring, which can allow more flexibility of the wound cover set 28 over the wound site 16 when the wound cover set 28 is attached to the skin 18. The spacer element 64 is configured to conform to the curves found in the human body, while maintaining adequate spacing between the drape 36 and the wound site 16.
    [0034] Other devices can also be used as a spacer element to adequately space the drape 36 from the wound site 16 when reduced pressure is being applied to the closed volume 42. Also, the capillary element 34 can be configured to provide voids suitable for gases found in the air, so that the pressure
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    Reduced 14/31 can be maintained. For example, the capillary element 34 can be produced from a relatively more rigid foam as compared to the drape 36 which holds gas voids, while absorbing exudate from the wound. The capillary element 34 can also be produced from the superabsorbent polymers described above which expand and form gas voids, for example, between adjacent spheres, to provide the aforementioned volume control.
    [0035] The wound cover assembly 28 may also include a wound drape release liner 70, which may be similar to the release linings used in known bandages. The wound drape release liner 70 is disposed on the bottom surface 44 of drape 36. The wound drape release liner 70 is removable to expose an adhesive 72 provided on the bottom surface 44 of drape 36. The wound drape 70 is removed from drape 36 prior to fixing the wound cover set 28 to the skin 18 and over the wound site 16.
    [0036] The wound cover assembly 28 may also include a gas-permeable liquid-impermeable membrane 78 that covers the opening 40 in the drape 36. In the embodiment illustrated in Figures 3 and 4, the gas-permeable liquid-impermeable membrane 78 is attached to the bottom surface 44 of the drape 36; however, the gas-permeable liquid-impermeable membrane 78 can also be arranged on the outer surface 46 of the drape 36 which covers the opening 40 in the drape 36, which is shown in Figure 5. The gas-permeable liquid-impermeable membrane 78 prevents the liquid (e.g., exudate) to move from the capillary element 34 through the opening 40 towards the pump set 30 when the pump set 30 is attached to the wound cover set 28, such as that
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    15/31 shown in Figure 4. With reference to Figure 5, when the gas-permeable liquid-impermeable membrane 78 is disposed on the outer surface 46 of the drapery 36, the gas-permeable liquid-impermeable membrane 78 can be connected with the drapery 36 using a releaseable adhesive to allow the subsequent removal and refixing of the gas-permeable liquid-impermeable membrane 78 to the drape 36, which may allow the addition or replacement of the capillary element 34. In the embodiment shown in Figure 5, the peeling layer 38 is connected with the drape 36 in such a way that removal of the peeling layer 38 does not result in the removal of the gas-permeable liquid impermeable membrane 78. For example, in Figure 5, the peeling layer 38 is larger than the impermeable membrane to gas permeable liquid 78, and connection between the peeling layer 38 and the drape 36 (for example, via adhesive, welding, or the like) is offset from an edge peripheral of the gas-permeable liquid-impermeable membrane 78, so that removal of the peeling layer 38 does not necessarily result in the removal of the gas-permeable liquid-impermeable membrane 78. [0037] The peeling layer 38 covers the opening 40 (or openings if more than one is provided) in the drape 36. Only one peeling layer 38 is shown in Figures 3-5, however, more than one peeling layer 38 can be provided. For example, Figure 6 represents a plurality of peeling layers 38 where each peeling layer 38 covers a respective opening 40 (not visible in Figure 6) in the drape 36. The peeling layer 38 can be produced from a thin flexible film. Examples of such materials include polyurethane and polyethylene films. The peeling layer 38 is configured to inhibit the passage of air and liquid through the peeling layer 38 when the peeling layer 38 is covering the opening 40 in the drape.
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    16/31
    36. The peeling layer 38 can be produced from a material that is impermeable to air and liquid, or the peeling layer 38 can be coated with a substance, for example, a hydrogel or hydrocolloid, or be metallized to be impervious to liquid. [0038] As mentioned above, the peeling layer 38 is releasable from the drape 36 when the drape 36 is in contact with the skin 18 and covers the wound site 16. When the peeling layer 38 is removed from the drape 36, opening 40 in drape 36 is exposed to the environment. When the drape 36 is impermeable to air and liquid, removal of the peeling layer 38 can transform the wound cover set 28 from an occlusive dressing to a non-occlusive dressing. With the peeling layer 38 removed from the drape 36, the pump set 30 can be attached to the wound cover set 28, or to the skin 18, to provide negative pressure to the wound site 16. With reference to Figure 6, one of the peeling layers 38 can be removed and covered by an adjustment connected with a mechanical pump (described in more detail below), and a second (or third, for example) peeling layer 38 can be removed, exposing the respective opening 40 covered by second (or third) peeling layer 38 to the environment. This can provide a breathable, non-occlusive dressing connected to a mechanical pump, which can be useful with larger wounds that generate a relatively larger amount of exudate.
    [0039] In the illustrated embodiment, the peeling layer 38 is shown as a separate layer from the drape 36 which is connected to the drape 36. The peeling layer 38 can be connected to the drape 36, via adhesive, welding, or other connection similar to around a periphery of the peeling layer 38 that would provide an air and liquid impermeable seal at the connection
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    17/31 between the stripping layer 38 and the draping 36. Alternatively, the stripping layer 38 can be a removable section of the draping 36. Classification lines can be cut into, but not across, the thickness of the drape 36 to define the peeling layer 38. [0040] Pump set 30 generally includes a pump 100 and a pump drape102. Pump drape 102 is configured to attach to drape 36 or skin 18 around wound site 16, and to cover opening 40 in drape 36 after peeling layer 38 has been removed from drape 36. Figure 2 represents the left side of the pump drape 102 attached to the skin 18 and the right side attached to the drape 36. The pump drape 102 can be made larger so that the pump drape 102 contacts the skin 18 and surrounds the peripheral edge 62 of the drape 36. Also, the pump drape 102 can be made smaller than the pump drape 102 which is attached only to the drape 36.
    [0041] The pump drape 102 includes a bottom side 104 and an outer side 106 opposite the bottom side 104. The bottom side 104 of the pump drape 102 is the side of the pump drape 102 that contacts the outer surface 46 of the drape 36 when the pump set 30 is attached to the wound cover set 28, or that contacts the skin 18 when the pump drape 102 is attached to the skin
    18. The outer side 106 of the pump drape 102 is exposed to the environment in the illustrated embodiment.
    [0042] Pump assembly 30 also includes a pump sealing element, which can include a pump gasket 108 or adhesive 110. Pump sealing element 108, 110 can be positioned on the bottom side 104 of the pump drape 102 Adhesive 110 can be an adhesive that is stronger or more aggressive than adhesive 72 on drapery 36, for example, when adhesive 110 only comes in contact with drapery 36, not the skin
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    18/31
    18. Pump gasket 108 can be produced from the same material, for example, a hydrogel, and operates similarly to sealing element 60. Pump gasket 108 can contact human skin 18, for example, when pump draining 102 is larger than the wound cover set 28. Pump sealing element 108, 110 is configured to prevent air from entering between pump drape 102 and drape 36 when pump drape 102 is attached to drape 36, or to prevent the ingress of air between the pump drape 102 and the skin 18 when the pump drape 102 is attached to the skin 18.
    [0043] Pump set 30 also includes a pump drape release liner 112 that covers the pump sealing element, which can be adhesive 110 or pump gasket 108. Pump drape release liner 112 is removed from the pump drape 102 before attaching the pump set 30 to the wound cover set 28, or to the skin 18.
    [0044] Pump 100 in pump set 30 can be a reactor configured to react with a selected gas found in the air, a zinc / air cell, a mechanical pump, or other small pumping device that can provide reduced pressure to the volume closed 42 through opening 40 when the pump set 30 is attached to the wound cover set 28. In an embodiment where the pump 100 is a reactor configured to react with a selected gas found in the air, the reactor consumes the gas selected in the closed volume 42. In the embodiment where pump 100 is such as a reactor, pump drape 102 covers pump 100. An example of a reactor that can be used in pump assembly 30 is described in US 2014 / 0109890A1. US 2014 / 0109890A1 describes an oxygen-based heater; however, the oxygen-based heater can be used as the reactor to consume
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    19/31 oxygen within the closed volume 42, thereby producing a partial vacuum within the closed volume 42. The reactor may include a reducing agent, a binding agent on a reactor substrate, and an electrolyte solution, which may be provided on an electrolyte-impregnated pad. The reducing agent in the reactor substrate can be zinc, aluminum, or iron, for example.
    [0045] The pump set 30 additionally includes a gas-permeable liquid-impermeable membrane 120, which may be similar to the gas-permeable liquid-impermeable membrane 78 that covers opening 40 in drape 36. In the embodiment where pump 100 is a oxygen-consuming reactor in closed volume 42, the reactor is interposed between the gas-permeable liquid-impermeable membrane 120 and the pump drape 102 when the pump drape 102 is attached to drape 36 which covers opening 40 in drape 36. A gas-permeable liquid-impermeable membrane 120 can also wrap the pump 100.
    [0046] Referring back to Figure 3, the pump assembly 30 may also include a removable seal layer 130 that prevents the reactor from being exposed to oxygen from the environment even after removal of the removable seal layer 130. In the embodiment where pump 100 is the reactor configured to react with oxygen, both the pump draining release liner 112 and the removable seal layer 130 are removed from pump assembly 30 before attachment of pump assembly 30 to the wound cover assembly 28, or to the skin 18. If desired, the pump drape release liner 112 can be attached to the removable seal layer 130 so that removal of the pump drape release liner 112 from the pump drape 102 results in removal of the removable seal layer 130 that exposes the reactor to the environment. In another alternative arrangement, the
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    20/31 pump draining release 112 can be attached to pump draining 102 in a way to prevent pump 100, which in this embodiment would be a reactor configured to consume oxygen, from being exposed to the environment until after removing only the pump drape release 112, for example, the removable seal layer 130 can not be provided.
    [0047] As mentioned above, the pump 100 can also be a zinc / air cell. When pump 100 is a zinc / air cell, the zinc / air cell can react with oxygen found in closed volume 42 (Figure 3) to remove oxygen within closed volume 42, thereby reducing pressure in the closed volume 42. In the embodiment where pump 100 is a zinc / air cell, which is shown in Figure 7, pump drape 102 covers pump 100. In the embodiment where pump 100 is a zinc / air cell, a circuit 140 having a normally open switch 142 (both of which are shown schematically in Figure 7) can be connected to an anode and cathode, respectively, in the zinc / air cell. An operator can press the pump drape 102, for example, in the vicinity of switch 142 to close switch 142. The zinc / air cell reacts with oxygen in closed volume 42 (Figure 3) to remove oxygen from closed volume 42, thereby reducing the pressure within the closed volume 42. With continued reference to Figure 7, the pump assembly 30 may also include the gas-permeable liquid impermeable membrane 120 and the removable sealing layer 130 that prevents the zinc cell / air from being exposed to oxygen from the environment until after removing the removable seal layer 130.
    [0048] In place of the reactor and zinc / air cell described above, pump 100 can be one or any combination of electrochemical pumps, vacuum demand devices (referred to here)
    Petition 870190090421, of 12/09/2019, p. 39/85
    21/31 as VOD), electrolyzers, pressure-reducing solid-state devices, oxygen-absorbing iron packs, or titanium zirconium, iron vanadium, lithium, lithium metal, magnesium, calcium, lithium combinations barium, zinc-air battery, zinc-air battery components, or other highly reactive materials with the selected gases, for example, nitrogen, carbon dioxide and oxygen gases found in wound bed environments.
    [0049] With reference back to Figure 3, the pump set 30 may additionally include at least one spacer element 160 covered by the pump drape 102. The spacer element 160 in the pump set 30 may be similar in configuration and function to the element spacer 64 provided in the wound cover assembly
    28. The spacer element 160 in the pump set 30 is configured to maintain spacing between the pump drape 102 and the drape 36 when reduced pressure is applied under the drape 36, that is, within the closed volume 42.
    [0050] Pump draining 102 covers pump 100, which can be a reactor, and spacer 160 to define a chamber 162 that maintains at least a predefined chamber volume, while gas is being consumed from the closed volume 42 Since drape 36 can be produced from a thin flexible elastomeric film, as gas is being consumed from the closed volume 42, drape 36 can be removed from the wound site 16 and adjacent skin, which can reduce the volume of the wound. closed volume 42. According to the ideal gas law, if the volume of closed volume 42 decreases, then the pressure in closed volume 42 will increase from a relative negative pressure (with respect to ambient pressure) towards ambient pressure. Since it is desirable to maintain a negative pressure relative to the ambient pressure around the wound site 16, an increase in
    Petition 870190090421, of 12/09/2019, p. 40/85
    22/31 pressure on the closed volume 42 towards the environment may be undesirable. By providing a chamber 162 having a predefined chamber volume, however, a total system volume, which includes closed volume 42 and predefined chamber volume, can be provided even if drapery 36 removes wound site 16, or the capillary element 34 begins to fill with exudate. In this way, the relative negative pressure can be maintained at the total system volume. This is because as gas is being consumed from both the closed volume 42 and from the chamber 162, the predefined chamber volume is maintained even if the closed volume 42 is reduced.
    [0051] The closed volume 42 is composed of a portion of solid volume occupied by the capillarity element 34, and a portion of air volume occupied by the air trapped in the closed volume 42. In the case of a therapeutic negative pressure system, used to wound care, the reported operating pressure range, relative to the standard atmospheric pressure of 760 mmHg, is from -60 mmHg to -200 mmHg (absolute pressures from 560 to 700 mmHg). Where pump 100 is a reactor configured to consume oxygen, after all of the oxygen molecules have been consumed by the air reactor in the total system volume, the gas pressure in the total system volume is reduced by 21% (or 159.6 mmHg), assuming that the total system volume was to remain constant. Thus, with the ideal case of maximum potential distribution of -159.6 mmHg with dry air (note that the presence of moisture can change this number), designating a system to distribute the correct operating pressure, taking taking into account changes in the volume of the closed volume 42 and exudate entering the capillary element 34 and air displacement, it is a formidable task.
    Petition 870190090421, of 12/09/2019, p. 41/85
    23/31 [0052] The negative pressure device 26 performs this task by dividing the negative pressure system into two parts: the wound cover set 28 (or bandage part) and the pump set 30. The cover set wound 28 (part of bandage) functions as a bandage in order to be flexible and absorb fluid (exudate) as needed. Additionally, the wound cover assembly 28, while connected to the pump assembly 30, works to prevent fluid movement between the two assemblies, while remaining in pneumatic communication. By absorbing the fluid (exudate) only in the wound cover set 28, the effect of volume loss, and thus pressure loss, on the system can be minimized. The materials that make up the wound cover set 28 can be soft and compatible, and the pump set 30 includes more rigid components to reduce loss of volume in the pump set 30 so as to increase the likelihood that the pressure in the total volume of the system remains in the therapeutic range. In view of the aforementioned, it is desirable to have the preset chamber volume to be at least six times as large as the initial air volume portion (before the reactor consumes oxygen in this example) of the closed volume 42.
    [0053] As discussed above, pump 100 can also be a mechanical pump. Such an embodiment is shown schematically in Figure 8. In the embodiment shown in Figure 8, the pump assembly 30 may additionally include a power source 150, which is electrically connected with the pump 100, and is also connected with the pump drape 102. In the embodiment where the pump 100 is a mechanical pump, a circuit 152 can be provided with a normally open switch 154. An operator can tighten the pump drape 102, for example, to close the
    Petition 870190090421, of 12/09/2019, p. 42/85
    24/31 switch 154 to supply power from the power source 150, which can be a small battery, to the pump 100. In the embodiment where the pump 100 is a mechanical pump, the one-way check valve 156 can be provided in the drained pump 102 to allow the gas to move from the closed volume 42 through the one-way check valve 156 in the environment; however, ambient air is prevented from passing through the check valve 156 towards the closed volume 42.
    [0054] The pump set 30 may also include an opening (similar to opening 40) in the pump drape 102 covered by a layer of the pump shell (similar to the shell layer 38). Removing the pump peel layer may expose the opening in the pump drape 102 to allow replacement of the pump 100. The pump peel layer would connect with the pump drape 102 in the same way as the peel layer 38 connects. with the drape 36. The pump stripping layer would be produced from the same material as the stripping layer 38.
    [0055] Another embodiment of a mechanical pump is shown in Figure 9. In this embodiment, pump 100 is connected to the pump drape 102 through a fluid line 170, and pump 100 is located externally from the pump drape. 102. A setting 172 passes through the pump draining 102, and the fluid line 170 connects setting 172, which includes an internal passage, to the pump 100. The pump 100 connects to a container 174 through an exhaust line. 176.
    [0056] Figure 10 represents another embodiment of a negative pressure device 226 including a wound cover assembly 228 and a pump assembly 230. The wound cover assembly 228 may be similar to the wound cover assembly 28 described above. , and includes a drape 236
    Petition 870190090421, of 12/09/2019, p. 43/85
    25/31 including an opening 240. Drape 236 is produced from a flexible material that inhibits the passage of liquid and air through drape 236 other than through opening 240. Drape 236 covers a capillarity element (not visible), which is similar to the capillary element described above 34. The wound cover assembly 228 is also provided with a sealing element (not visible), which is similar in construction and function to the sealing element 60 described above. The sealing element surrounds the capillarity element, and when applied to the skin it cooperates with draping 236 to define a closed volume (similar to the closed volume described above 42) covered by draping 236 and surrounded by the sealing element. Air inside the closed volume is inhibited from leaving the closed volume other than through opening 240.
    [0057] The pump set 230 includes a pump 300, which is a reactor configured to react with a gas found in the air to consume the gas in the illustrated embodiment. The reactor is positioned inside a chamber 302 that is in fluid communication with the closed volume defined by the wound cover assembly 228, via opening 240. In the embodiment shown in Figure 10, there is a rigid container 304 that is in communication fluid with the closed volume, and defines chamber 302. Chamber 302, similar to chamber 162 described above, is configured to maintain a predefined chamber volume, while the gas being consumed by the reactor is being consumed from the closed volume. Consequently, if the closed volume decreases in volume as the gas in the closed volume is being consumed, the preset chamber volume is maintained.
    [0058] In Figure 10, a connector 310 mechanically connects the rigid container 304 with the wound cover assembly 228, and pneumatically connects chamber 302 with the closed volume. a
    Petition 870190090421, of 12/09/2019, p. 44/85
    26/31 air-permeable liquid-impermeable element (not visible in Figure 10, but similar to the gas-permeable liquid-impermeable membrane 120 described above) is interposed between chamber 302 and the closed volume, and is configured to avoid the liquid ( exudate) withdrawn in the closed volume from entering chamber 302. As such, the absorption fluid (exudate) only in the wound cover set 228, the effect of loss of volume, and thus loss of pressure, can be minimized , in the total system.
    [0059] Rigid vessel 304 in Figure 10 may include claw recesses 312 in which rigid vessel 304 may be tightened or depressed to activate the reactor such that after activation of the reactor it begins to consume a selected air gas inside chamber 302 and the closed volume. For example, by tightening the rigid container 304 in the claw recesses 312, a sealing layer that prevents the reactor from being exposed to the environment can be perforated, thereby exposing the reactor to air. Other ways in which the reactor can be activated will be described in more detail.
    [0060] Figure 11 represents a pump set 330 that includes a pump 340, which is a reactor configured to react with a gas found in the air to consume the gas. The reactor is positioned inside a chamber 342 defined by a rigid container 344. A connector 346, which is similar to connector 310, can mechanically connect the rigid container 344 with a wound cover assembly, such as the wound cover assembly 228 in Figure 10, and pneumatically connects chamber 342 to the closed volume defined by the wound cover assembly. Chamber 342, similar to chamber 162 described above, is configured to maintain a predefined chamber volume, while the gas being consumed by the reactor is being consumed from the closed volume defined by the wound cover set to which the
    Petition 870190090421, of 12/09/2019, p. 45/85
    27/31 pump set 330 is connected. The rigid container 344 may include a lid 350 which rests on a base 352. The reactor can be activated by rotating the lid 350 with respect to the base 352.
    [0061] Figure 12 represents a pump set 370 that includes a pump 380, which is a reactor configured to react with a gas found in the air to consume the gas. The reactor is positioned inside a chamber 382 defined by a rigid container 384. A connector similar to connector 310 can mechanically connect the rigid container 384 with a wound cover assembly, such as wound cover assembly 228 in Figure 10, and pneumatically connect chamber 382 to the closed volume defined by the wound cover assembly. Chamber 382, similar to chamber 162 described above, is configured to maintain a predefined chamber volume, while gas being consumed by the reactor is being consumed from the closed volume defined by the wound cover set to which the pump set 370 is connected. The rigid container 384 may include a lid 390 hingedly connected to a base 392. To activate the reactor, lid 390 is hinged with respect to base 392 to expose the reactor. If the reactor is covered by a removable seal layer that prevents the reactor from being exposed to the environment even after removal of the removable seal layer, then the removable seal layer can be removed when the cover 390 is hinged away from the base 392. After activation of the reactor, cover 390 closes and seals against base 392 to define chamber 382.
    [0062] Figure 13 represents a pump set 430 that includes a pump (not visible), which is a reactor configured to react with a gas found in the air to consume the gas. The reactor is positioned inside a chamber 432 defined by a rigid container 434. A connector similar to connector 310 can connect
    Petition 870190090421, of 12/09/2019, p. 46/85
    28/31 mechanically rigid container 434 with a wound cover assembly, such as wound cover assembly 228 in Figure 10, and pneumatically connect chamber 432 with the closed volume defined by the wound cover assembly. Chamber 432, similar to chamber 162 described above, is configured to maintain a predefined chamber volume, while gas being consumed by the reactor is being consumed from the closed volume defined by the wound cover set to which pump set 430 is connected. An actuator 436 can move relative to the rigid container 434 to activate the reactor. For example, to activate the reactor, actuator 436 slides relative to rigid container 434. Actuator 436 can connect with a cutting element to cut through a sealing layer that prevents the reactor from being exposed to the environment until after sealing layer has been punctured.
    [0063] A method of treating the wound site 16 will be described with reference to the wound cover set 28 shown in Figure 3 and the pump sets 30 shown in Figures 3, 4 and 7 - 9. Nevertheless, the method of Treatment of wound site 16 can be carried out using a wound cover set that is structurally different than the wound cover set 28 shown in Figure 3, or a pump set that is structurally different than the represented pump sets 30.
    [0064] The method of treating the wound site 16 includes placing the lower surface 44 of the drape 36 of the wound covering set 28 on the skin 18 surrounding the wound site 16. The drape 36 includes the opening 40. The method it may additionally include removing the peeling layer 38 from the drape 36 to expose the opening 40 to the environment. The method also includes
    Petition 870190090421, of 12/09/2019, p. 47/85
    29/31 fix pump set 30 to drape 36 or to skin 18, to cover opening 40 in drape 36. Where the pump set includes a reactor or zinc / air cell configured to react with a selected gas found in the air and the removable seal layer 130 which prevents the reactor or zinc / air cell from being exposed to the environment even after removing the removable seal layer, the method may additionally include removing the removable seal layer 130, and exposing the pump 100 to the environment prior to attaching pump set 30 to drapery 36, or to skin 18. Where the pump set includes a zinc / air cell such as pump 100, the method may include closing electrical circuit 140 (Figure 7), which includes the zinc / air cell. Also, in the embodiment where the pump assembly includes a mechanical pump such as pump 100, the method may also include closing electrical circuit 152, which includes mechanical pump and power source 150.
    [0065] Controlling the volume around the wound site 16 can be important to maintain negative pressure. Both the drape 36 and the pump drape 102 can be produced from thin films that can collapse towards the wound site 16 as gas is being removed from around the wound site. Spacer elements 64, 160 can maintain adequate spacing between drapes 36, 102 and the wound site 16, or skin 18 when reduced pressure is applied under drapes 36, 102.
    [0066] Also, in some examples, the peeling layer 38 may not be provided. In examples where the peeling layer 38 is not provided, the negative pressure device 26 may still have a two-piece design, for example, it includes the wound cover assembly 28 and the pump assembly30. In examples where the peeling layer 38 is not provided, the drape 36 may include the
    Petition 870190090421, of 12/09/2019, p. 48/85
    30/31 opening 40 (or multiple openings) that are covered by the pump drape 102 and the remainder of the pump set 30. In examples where the peeling layer 38 is not provided, the drape 36 can also be produced from a material that allows gas to permeate through drape 36.
    [0067] Alternatively, the negative pressure device 26 may have a one-piece design without the peeling layer 38. In such an example, the wound contact element, which may include the wound contact layer 32 or the capillary 34, a drape (for example, an external drape similar to the pump drape 102), the pump 100 and the spacer element (for example, similar to the spacer element 64, 160) can be provided as a set that is attached to the skin 18 as a unit. In this example, an internal drape (similar to drape 36 in Figure 4) may not be provided. In this alternative arrangement, the drape is configured to inhibit the passage of air and liquid through the drape. In this alternative arrangement, a sealing element, which is similar to the sealing element 60 described above, can be positioned on a skin contact side of the wound contact element, or on a bottom surface of the drape. In this alternative arrangement, the pump is draped, and can be any of the pumps described above. In this alternative arrangement, the negative pressure device 26 may include a gas-permeable liquid-impermeable membrane, similar to the gas-permeable liquid-impermeable membrane 120. Where the pump is a reactor, described above, the pump is interposed between the impermeable membrane the gas permeable liquid and the drape when the drape is attached to the skin 18 covering the wound site 16. In this alternative arrangement where the pump is a reactor, the negative pressure device may also include a removable sealing layer that prevents the reactor to be exposed to the environment until after
    Petition 870190090421, of 12/09/2019, p. 49/85
    31/31 removal of the removable seal layer. In this alternative arrangement, the negative pressure device 26 may also include a release liner disposed on a bottom surface of the drape, and the release liner is removable to expose an adhesive provided on a bottom surface of the drape.
    [0068] Embodiments of a negative pressure device and methods of treating an injury site have been described above in particular. Modifications and changes will occur to those technicians in the subject after reading and understanding the previous detailed description. The invention, however, is not limited to only the embodiments described above. Instead, the invention is broadly defined by the appended claims and their equivalents. It will be appreciated that several of the above features and functions, or alternatives or varieties thereof, can be desirably combined in many other different systems or applications. Also, that several currently unanticipated or unanticipated alternatives, modifications, variations or improvements to them can subsequently be made by those skilled in the art who are also expected to be involved in the following claims.
    权利要求:
    Claims (15)
    [1]
    1. Negative pressure device characterized by the fact that it comprises:
    a drape including an opening and being produced from a flexible material that inhibits the passage of liquid and air through the drape other than through the opening;
    a capillarity element covered by the drape;
    a sealing element that surrounds the capillarity element, and when applied to the skin, it cooperates with the drape to define a closed volume covered by the drape, and surrounded by the sealing element, such that the air within the closed volume is inhibited from leaving the closed volume other than through opening;
    a reactor configured to react with a gas found in the air to consume the gas; and a chamber in fluid communication with the reactor and the closed volume, via the opening, the chamber configured to maintain a predefined chamber volume while gas is being consumed from the closed volume.
    [2]
    2. Negative pressure device, according to claim 1, characterized by the fact that it additionally comprises a pump drape that covers the reactor and spacer element positioned in the chamber between the pump drape and the drape to maintain the spacing between the drape of pump and drape when reduced pressure is applied under the drape.
    [3]
    3. Negative pressure device according to claim 2, characterized by the fact that the closed volume includes a portion of solid volume occupied by the capillarity element, and a portion of air volume occupied by the air trapped in the closed volume, in the what the default camera volume is at
    Petition 870190090421, of 12/09/2019, p. 66/85
    2/4 minus six times the volume of air before the reactor consumes the gas.
    [4]
    4. Negative pressure device according to claim 2 or 3, characterized in that the pump drape is flexible film material.
    [5]
    5. Negative pressure device according to claim 1, characterized by the fact that it additionally comprises a rigid container in fluid communication with the closed volume, and defining the chamber.
    [6]
    6. Negative pressure device according to claim 5, characterized by the fact that the closed volume includes a portion of solid volume occupied by the capillarity element, and a portion of initial air volume occupied by the air trapped in the closed volume before of the reactor to consume gas, in which the preset chamber volume is at least six times greater than the initial air volume portion.
    [7]
    7. Negative pressure device according to claim 1, characterized in that it additionally comprises a removable layer or portion that covers the opening, the removable layer or portion being configured to inhibit the passage of air and liquid through the removable layer or portion, and draping other than through the opening after the removable layer or portion has been removed to expose the opening to the environment.
    [8]
    Negative pressure device according to claim 1, characterized in that it additionally comprises a wound covering membrane and a wound covering membrane release liner disposed on a lower surface of the wound covering membrane, the coating release liner
    Petition 870190090421, of 12/09/2019, p. 67/85
    3/4 wound being removable from the wound covering membrane to expose an adhesive and the sealing element provided on the bottom surface of the wound covering membrane.
    [9]
    9. Negative pressure device, according to claim 1, characterized by the fact that the reactor is configured to consume oxygen.
    [10]
    10. Negative pressure device, according to claim 9, characterized by the fact that the reactor is configured to consume nitrogen.
    [11]
    11. Negative pressure device according to claim 1, characterized by the fact that the drape is configured to be removed from the capillarity and skin element when the reduced pressure is applied under the drape.
    [12]
    12. Method of treatment of a tissue site, characterized by the fact that it comprises:
    attach a drape to the skin surrounding a fabric location, and covers a capillarity element, the drape including an opening and being produced from a flexible material that inhibits the passage of liquid and air through the drape other than through the opening;
    seal around the fabric location with a sealing element that cooperates with the drape to define a closed volume covered by the drape and surrounded by the sealing element;
    providing a reactor configured to react with a gas found in the air to consume the gas; and connecting a chamber to be in fluid communication with the reactor and the closed volume, where the chamber is configured to maintain a predefined chamber volume while the reactor consumes gas in the closed volume.
    Petition 870190090421, of 12/09/2019, p. 68/85
    4/4
    [13]
    13. Method according to claim 12, characterized by the fact that the reactor further includes providing the reactor in the chamber.
    [14]
    14. Method according to claim 12 or 13, characterized in that it additionally comprises:
    remove a removable seal layer and expose the reactor to the environment.
    [15]
    15. Method according to claim 12 or 13, characterized by the fact that it additionally comprises:
    cover the chamber with a pump drape, which is produced from a flexible film material.
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    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US4875473A|1986-04-03|1989-10-24|Bioderm, Inc.|Multi-layer wound dressing having oxygen permeable and oxygen impermeable layers|
    US5060642A|1990-01-05|1991-10-29|Gilman Thomas H|Wound dressing with air permeable bacteria impermeable reservoir|
    US5533962A|1995-05-12|1996-07-09|Peterman; Shadi|Ringless adhesive bandage|
    AT320781T|2001-11-23|2006-04-15|Coloplast As|WOUND DRESSING|
    US7361184B2|2003-09-08|2008-04-22|Joshi Ashok V|Device and method for wound therapy|
    US7779625B2|2006-05-11|2010-08-24|Kalypto Medical, Inc.|Device and method for wound therapy|
    US8808274B2|2007-11-21|2014-08-19|Smith & Nephew Plc|Wound dressing|
    ES2702298T3|2007-11-21|2019-02-28|Smith & Nephew|Wound dressing|
    EP2345437B1|2008-03-05|2014-04-23|KCI Licensing, Inc.|Dressing for applying reduced pressure to and collecting and storing fluid from a tissue site|
    ES2752806T3|2008-05-27|2020-04-06|Smith & Nephew Inc|Negative pressure wound therapy device|
    JP5547197B2|2008-09-18|2014-07-09|ケーシーアイライセンシングインコーポレイテッド|Multilayer dressing, system, and method for applying reduced pressure to a tissue site|
    CA2741737C|2008-10-29|2014-09-09|Kci Licensing, Inc.|Reduced-pressure, deep-tissue closure systems and methods|
    WO2010068502A1|2008-11-25|2010-06-17|Spiracur Inc.|Device for delivery of reduced pressure to body surfaces|
    DE102009031992A1|2009-07-06|2011-01-13|Paul Hartmann Ag|Device for negative pressure therapy of wounds|
    US8821458B2|2010-04-16|2014-09-02|Kci Licensing, Inc.|Evaporative body-fluid containers and methods|
    US9061095B2|2010-04-27|2015-06-23|Smith & Nephew Plc|Wound dressing and method of use|
    EP2417947A1|2010-08-12|2012-02-15|John Bennett|Integrated contoured negative pressure bandages|
    MX347742B|2010-09-20|2017-05-10|Smith & Nephew|Negative pressure device.|
    US8439894B1|2011-03-07|2013-05-14|Larry W. Miller|Negative pressure bandage with internal storage chamber|
    CN105963074B|2011-07-14|2020-01-17|史密夫及内修公开有限公司|Wound dressing and method of treatment|
    CA2841860C|2011-08-03|2020-12-15|Kci Licensing, Inc.|Reduced-pressure wound dressings|
    DE102011082341A1|2011-09-08|2013-03-14|Paul Hartmann Ag|Connection device for use in the vacuum treatment of wounds|
    CN104168865B|2012-03-28|2016-10-26|凯希特许有限公司|Assist the depressurized system separated with clinical parts of electronics, apply part and method|
    CN104768504A|2012-10-19|2015-07-08|充电电池公司|Electrolyte formulations for oxygen activated portable heater|
    GB201222770D0|2012-12-18|2013-01-30|Systagenix Wound Man Ip Co Bv|Wound dressing with adhesive margin|
    EP3238674B1|2013-03-14|2019-01-30|KCI Licensing, Inc.|Absorbent dressing with hybrid drape|
    WO2015054040A1|2013-10-07|2015-04-16|Scherson Daniel|Electrochemical method and apparatus for forming a vacuum in a sealed enclosure|
    US10583228B2|2015-07-28|2020-03-10|J&M Shuler Medical, Inc.|Sub-atmospheric wound therapy systems and methods|
    CN105147344B|2015-10-19|2018-12-21|张新平|Skin wound assists device for healing|JP6703125B2|2015-10-30|2020-06-03|ロレン・カウンティー・コミュニティー・カレッジ・イノヴェイション・ファウンデイション|Wound treatment device and method|
    WO2017191154A1|2016-05-03|2017-11-09|Smith & Nephew Plc|Negative pressure wound therapy device activation and control|
    JP2019526322A|2016-08-25|2019-09-19|スミス アンド ネフュー ピーエルシーＳｍｉｔｈ ＆ Ｎｅｐｈｅｗ Ｐｕｂｌｉｃ Ｌｉｍｉｔｅｄ Ｃｏｍｐａｎｙ|Absorbable negative pressure wound therapy dressing|
    WO2018162613A1|2017-03-08|2018-09-13|Smith & Nephew Plc|Negative pressure wound therapy device control in presence of fault condition|
    WO2018206420A1|2017-05-09|2018-11-15|Smith & Nephew Plc|Redundant controls for negative pressure wound therapy systems|
    US11007083B2|2018-08-28|2021-05-18|Aatru Medical, LLC|Dressing|
    JP2021534854A|2018-08-28|2021-12-16|アートラ・メディカル、エルエルシーAatru Medical, Llc|Negative pressure device with oxygen scavenger and volume reduction|
    EP3829689A1|2018-08-29|2021-06-09|Aatru Medical, LLC|Negative pressure treatment including mechanical and chemical pump|
    USD898925S1|2018-09-13|2020-10-13|Smith & Nephew Plc|Medical dressing|
    WO2020106383A1|2018-11-20|2020-05-28|Aatru Medical, LLC|Negative pressure device including expandable segment|
    US11083833B1|2019-02-28|2021-08-10|Aatru Medical, LLC|Chemical pump housing for negative pressure system|
    WO2021011181A1|2019-07-17|2021-01-21|Aatru Medical, LLC|Negative pressure device for articulating joint|
    AU2020322459A1|2019-07-30|2022-02-10|Advanced Dressings, LLC|Dressing for providing low oxygen environment|
    US10828202B1|2019-10-03|2020-11-10|Aatru Medical, LLC|Negative pressure treatment including mechanical and chemical pump|
    US10881553B1|2019-10-03|2021-01-05|Advanced Dressing, LLC|Reduced pressure device having selectively deliverable electrolyte|
    WO2021257508A1|2020-06-16|2021-12-23|Advanced Dressing, LLC|Controlled oxygen dressing|
    法律状态:
    2021-10-19| B350| Update of information on the portal [chapter 15.35 patent gazette]|
    优先权:
    申请号 | 申请日 | 专利标题
    US15/478,327|US10046095B1|2017-04-04|2017-04-04|Wound therapy device and method|
    PCT/US2018/025980|WO2018187394A1|2017-04-04|2018-04-04|Negative pressure device and method|
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